RAMEN - Regional Association of Methylome variability with the Exposome and geNome

RAMEN is an R package which goal is to identify Variable Methylated Loci (VML) in microarray DNA methylation data. Then, using genome and exposome data, RAMEN identifies which individual genetic (G) or environmental (E) or joint (G+E or GxE) model better explains the VML variability. This package provides estimates of genetic and environmental contribution for each VML, allowing researchers to gain insights into the complex interplay between genetics, environment and DNA methylation.